Photomedicine with Inorganic Complexes: A Bright Future

نویسندگان

چکیده

Photo-induced reactions have the potential to revolutionize fields of photomedicine and intelligent drug delivery by providing means specifically inducing a chemical transformation in biological environments. The molecule that absorbs light engages photo-induced is called photosensitizer, key component this process. It transforms photon energy into variety reactions, such as photosensitized oxidations photodynamic therapy (PDT) ligand exchange photoactivated chemotherapy (PACT). Ruthenium complexes, particular, offer possibility maximize fine-tune each these changing electronic properties, hydrophobicity, steric hindrance ligands, thus affecting reactivity excited states. field has advanced immensely last decade we aim here report on major achievements ruthenium compounds for phototherapy. We will also discuss mechanism light-induced toxicity, upconverting systems activation type drugs, well initial steps towards commercial applications complexes PDT agents.

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ژورنال

عنوان ژورنال: Springer handbooks

سال: 2022

ISSN: ['2522-8706', '2522-8692']

DOI: https://doi.org/10.1007/978-3-030-63713-2_34